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SML1554

Sigma-Aldrich

S3QEL 2

동의어(들):

1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

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About This Item

실험식(Hill 표기법):
C19H25N5
CAS Number:
Molecular Weight:
323.44
UNSPSC 코드:
12352200
NACRES:
NA.77
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도움 문의

양식

powder

Quality Level

색상

white to beige

solubility

DMSO: 5 mg/mL, clear

저장 온도

−20°C

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 4

이 품목
RFA452411K-EPRFA4530113-EPRF45645P-EP
compatibility

for use with centrifuge models 5430/5430R

compatibility

for use with centrifuge models 5430/5430R

compatibility

for use with centrifuge models 5430/5430R

compatibility

for use with centrifuge models 5430/5430R

manufacturer/tradename

Eppendorf® 022654004 (NA), Eppendorf® 5427712003 (EU)

manufacturer/tradename

Eppendorf® 022654128 (NA), Eppendorf® 5427752005 (EU)

manufacturer/tradename

Eppendorf® 022654047 (NA), Eppendorf® 5427753001 (EU)

manufacturer/tradename

Eppendorf® 022654209 (NA), Eppendorf® 5427714006 (EU)

feature

lid, fixed angle rotor, to hold 30 x 1.5/2.0 mL tubes, non aerosol tight

feature

lid, to hold 24 x spin columns, aerosol-tight, fixed angle rotor

feature

lid, to hold 30 x 1.5/2.0 mL tubes, aerosol tight, fixed angle rotor

feature

lid, to hold 64 x 0.2 mL PCR tubes, non aerosol tight, strip rotor

parameter

20,817 × g max. RCF

parameter

19,090 × g max. RCF

parameter

20,817 × g max. RCF

parameter

13,543 × g max. RCF

packaging

pack of 1 ea

packaging

pack of 1 ea

packaging

pack of 1 ea

packaging

pack of 1 ea

technique(s)

centrifugation: suitable

technique(s)

centrifugation: suitable

technique(s)

centrifugation: suitable

technique(s)

PCR: suitable, centrifugation: suitable

생화학적/생리학적 작용

S3QEL 2 is a selective inhibitor of superoxide production from the outer Q-binding site of mitochondrial respiratory complex site III (IIIQo) without altering oxidative phosphorylation.
S3QEL 2 is a selective inhibitor of superoxide production from the outer Q-binding site of mitochondrial respiratory complex site III (IIIQo) without altering oxidative phosphorylation. Site IIIQo is the primary source of mitochondrial reactive oxygen species (ROS) and has been implicated in a broad range of ROS-mediated signaling and pathology. S3QEL 2 lowered HIF-1α induction, protected against ROS-induced, JNK-mediated cell stress in pancreatic beta-cells, and decreased the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets.
S3QEL 2, a cell permeable substituted allopurinol, is also known as 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine.[1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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