SML1713

Carprofen

≥97% (HPLC)

• 동의어(들): 6-Chloro-α-methyl-9H-carbazole-2-acetic acid
• 실험식(Hill 표기법): C₁₅H₁₂ClNO₂
• CAS Number: 53716-49-7
• Molecular Weight: 273.71
• EC Number: 258-712-4
• MDL number: MFCD00079028
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329826035
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23
• InChI: 1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)
• InChI key: PUXBGTOOZJQSKH-UHFFFAOYSA-N
• 유전자 정보: human ... PTGS2(5743)

설명

생화학적/생리학적 작용

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition with selectivity for COX-2 inhibition, while its antimicrobial activity is less certain. Carprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown carprofen can target the Escherichia coli DNA polymerase III β subunit.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3