로그인조직 및 계약 가격 보기
About This Item
실험식(Hill 표기법):
C14H15BrN2OS
CAS Number:
Molecular Weight:
339.25
UNSPSC 코드:
12352200
NACRES:
NA.77
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
O=C(C1=CC(C=CC=C2Br)=C2S1)N[C@@H]3CCCNC3
InChI
1S/C14H15BrN2OS/c15-11-5-1-3-9-7-12(19-13(9)11)14(18)17-10-4-2-6-16-8-10/h1,3,5,7,10,16H,2,4,6,8H2,(H,17,18)/t10-/m1/s1
InChI key
LRYYPTVUWGMZQB-SNVBAGLBSA-N
생화학적/생리학적 작용
Br-PBTC is a selective and potent type II positive allosteric modulator (PAM) that potentiates the opening of the nicotinic acetylcholine receptors (nAChR) subtypes containing α4β2, α2β2 and α2β4 subunits. Br-PBTC potentiates opening and reactivates desensitized (α4β2)2α4 nAChRs. It appears that Br-PBTC interacts with extracellular C-terminus of α2 or α4 in association with nearby parts of the α subunit.
selective and potent type II PAM that potentiates the opening of the nAChR subtypes containing α4β2, α2β2 and α2β4 subunits.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.