Name: Ticarcillin disodium salt
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₁₅H₁₄N₂Na₂O₆S₂

CAS Number:

4697-14-7

Molecular Weight:

428.39

MDL number:

MFCD07787410

UNSPSC 코드:

51282427

PubChem Substance ID:

24900306

NACRES:

NA.85

기술 서비스

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도움 문의

생물학적 소스

semisynthetic

Quality Level

200

양식

powder or crystals

색상

white to light yellow

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C([O-])=O)c3ccsc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7-,8-,9+,12-;;/m1../s1

InChI key

ZBBCUBMBMZNEME-QBGWIPKPSA-L

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일반 설명

Chemical structure: ß-lactam

애플리케이션

Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis.

생화학적/생리학적 작용

Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by ß-lactamases.