Name: Astec<SUP>&#174;</SUP> CHIROBIOTIC<SUP>&#174;</SUP> T Chiral (5 μm) HPLC Columns
Brand: SUPELCO

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About This Item

UNSPSC 코드:

41115700

eCl@ss:

32110501

NACRES:

SB.52

기술 서비스

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Product Name

Astec^® CHIROBIOTIC^® T Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 10 mm

material

stainless steel column

Quality Level

100

Agency

suitable for USP L63

설명

HPLC column

제품 라인

Astec^®

포장

pkg of 1 ea

제조업체/상표

Astec^®

파라미터

0-45 °C temperature
241 bar pressure (3500 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

25 cm × 10 mm

Matrix

High-purity silica gel particle platform
fully porous particle

기질 활성군

teicoplanin glycopeptide phase

입자 크기

5 μm

공극 크기

100 Å

작동 pH 범위

3.8-6.8

분리 기술

chiral

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일반 설명

CHIROBIOTIC^® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC^® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC^® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

Bonded phase: Teicoplanin
Operating pH range: 3.8 - 6.8
Particle diameter: 5, 10 or 16 μm
Pore size: 100 Å (CHIROBIOTIC^® T) or 200 Å (CHIROBIOTIC^® T2)

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature

애플리케이션

Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples.: This study outlines the development of a chiral LC-MS/MS method utilizing the Astec^® CHIROBIOTIC^® T Chiral HPLC Column for detecting salbutamol enantiomers in urine, showcasing its application in doping control and analytical chemistry. The research demonstrates the column′s capability for precise and selective measurement of chiral molecules in complex biological matrices (Chan et al., 2016).

High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: Highlighting the versatility of Astec^® CHIROBIOTIC^® T Chiral HPLC Column, this paper details the enantioseparation of cyclic amino acids critical for the development of new pharmaceuticals and biochemical studies. The column′s effectiveness in resolving complex chiral acids reinforces its importance in pharmaceutical research and chiral chemical analysis (Berkecz et al., 2009).