ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
Sinónimos:
SRK, STCD, STD, TZK, ZAP-70
Especie:
Human ZAP70 (7535), Mouse Zap70 (22637), Rat Zap70 (301348), Zebrafish zap70 (553615), domestic cat ZAP70 (101097059), dog ZAP70 (100271860), chicken ZAP70 (420086), cow ZAP70 (504509), sheep ZAP70 (101112639), Domestic Rabbit ZAP70 (100342021) ...Más
ID UniProtKB:
ID del gen:
- Human(7535) Summary: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(22637) zeta-chain (TCR) associated protein kinase
- Rat(301348) zeta-chain (TCR) associated protein kinase 70
- Zebrafish(553615) zeta-chain (TCR) associated protein kinase
- domestic cat(101097059) zeta-chain (TCR) associated protein kinase 70kDa
- dog(100271860) zeta-chain (TCR) associated protein kinase 70kDa
- chicken(420086) zeta-chain (TCR) associated protein kinase 70kDa
- cow(504509) zeta-chain (TCR) associated protein kinase 70kDa
- sheep(101112639) zeta-chain (TCR) associated protein kinase 70kDa
- Domestic Rabbit(100342021) zeta-chain (TCR) associated protein kinase 70kDa
- naked mole-rat(101716577) zeta-chain (TCR) associated protein kinase 70kDa
- domestic guinea pig(100713473) zeta-chain (TCR) associated protein kinase 70kDa
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ELISA
Product Number
Descripción
Especie
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-p-ZAP-70 (Tyr319) Antibody, clone 1B10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, monkey, mouse, rat
Aplicación
flow cytometry
immunocytochemistry
immunohistochemistry
peptide synthesis
western blot
immunocytochemistry
immunohistochemistry
peptide synthesis
western blot
Anti-ZAP70 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-p-ZAP-70 (Tyr493) Antibody, clone 1F10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-phospho-ZAP70 (pTyr319) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot
western blot
Anti-ZAP-70 Antibody, clone 1D9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Proteins
Product Number
Descripción
Especie
ZAP-70 Tyrosine Kinase human, ≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg,
Especie
human