144487

2-Amino-3-benzyloxypyridine

99%

• Empirical Formula (Hill Notation): C₁₂H₁₂N₂O
• CAS Number: 24016-03-3
• Molecular Weight: 200.24
• EC Number: 245-983-9
• MDL number: MFCD00006316
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848659
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• mp: 92-94 °C (lit.)
• functional group: phenyl
• SMILES string: Nc1ncccc1OCc2ccccc2
• InChI: 1S/C12H12N2O/c13-12-11(7-4-8-14-12)15-9-10-5-2-1-3-6-10/h1-8H,9H2,(H2,13,14)
• InChI key: NMCBWICNRJLKKM-UHFFFAOYSA-N
• Gene Information: human ... MAPK14(1432)

Description

General description

2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one.

Application

2-Amino-3-benzyloxypyridine was used in the synthesis of 1-acetyl-2-[2-(3-benzyloxypyridinyl)]iminoimidazolidine.

Biochem/physiol Actions

2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves