202495

Poly(ethylene glycol) methyl ether

average M_N 750, methoxy, hydroxyl

• Synonym(s): Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
• Linear Formula: CH₃(OCH₂CH₂)_nOH
• CAS Number: 9004-74-4
• MDL number: MFCD00084416
• UNSPSC Code: 12162002
• PubChem Substance ID: 24852093
• NACRES: NA.23

Properties

• Product Name: Poly(ethylene glycol) methyl ether, average M_n 750
• vapor density: >1 (vs air)
• Quality Level: 200
• vapor pressure: 0.05 mmHg ( 20 °C)
• form: paste; solid
• mol wt: average M_n 750
• refractive index: n20/D 1.459
• viscosity: 10.5 cSt(210 °F)(lit.)
• transition temp: T_m 30 °C
• density: 1.094 g/mL at 25 °C
• Ω-end: hydroxyl
• α-end: methoxy
• SMILES string: O(CCO)C
• InChI: 1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
• InChI key: XNWFRZJHXBZDAG-UHFFFAOYSA-N

Description

Application

Poly(ethylene glycol) methyl ether can be used:

• As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
• As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
• To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 359.6 °F - closed cup
• Flash Point(C): 182 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves