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241067

Sigma-Aldrich

2-Methoxyethylamine

99%

Synonym(s):

2-Aminoethyl methyl ether

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About This Item

Linear Formula:
CH3OCH2CH2NH2
CAS Number:
Molecular Weight:
75.11
Beilstein:
741854
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.406 (lit.)

bp

95 °C (lit.)

density

0.864 g/mL at 25 °C (lit.)

functional group

amine
ether

SMILES string

COCCN

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

General description

Kinetics of reaction of 2-methoxyethylamine with guanosine 5′-phospho-2-methylimidazolide (2-MeImpG) was studied[1].

Application

2-Methoxyethylamine can be used as a reactant:
  • In the substitution reaction with phosphoimidazolide-activated derivatives of nucleosides[1].
  • To synthesize amides by reacting with carboxylic acids[2].
  • For the chemical modification of α-acrylated cross-linked polymer via aza-Michael addition[3].

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1 of 4

This Item
8.18872291145225088
assay

99%

assay

≥98.0% (GC)

assay

97%

assay

97%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

bp

95 °C (lit.)

bp

95 °C/1013 hPa

bp

36-37 °C (lit.)

bp

-

form

liquid

form

liquid

form

-

form

-

density

0.864 g/mL at 25 °C (lit.)

density

0.87 g/cm3 at 20 °C

density

0.688 g/mL at 25 °C (lit.)

density

-

refractive index

n20/D 1.406 (lit.)

refractive index

n20/589 1.4594

refractive index

n20/D 1.374 (lit.)

refractive index

-


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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

53.6 °F

Flash Point(C)

12 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves


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Mesoporous Structured Silica-An improved catalyst for direct amide synthesis and its application to continuous flow processing.
Comerford J, et al.
ARKIVOC (Gainesville, FL, United States) (2012)
Nathan J Van Zee et al.
Nature, 558(7708), 100-103 (2018-06-01)
Water directs the self-assembly of both natural1,2 and synthetic3-9 molecules to form precise yet dynamic structures. Nevertheless, our molecular understanding of the role of water in such systems is incomplete, which represents a fundamental constraint in the development of supramolecular
A Kanavarioti et al.
The Journal of organic chemistry, 60(3), 632-637 (1995-02-10)
Aliphatic amines react with phosphoimidazolide-activated derivatives of guanosine and cytidine (ImpN) by replacing the imidazole group. The kinetics of reaction of guanosine 5'-phospho-2-methylimidazolide (2-MeImpG) with glycine ethyl ester, glycinamide, 2-methoxyethylamine, n-butylamine, morpholine, dimethylamine (Me2NH), ethylmethylamine (EtNHMe), diethylamine (Et2NH), pyrrolidine, and