283746

4-(Aminomethyl)benzoic acid

97%, for peptide synthesis

• Synonym(s): PAMBA
• Linear Formula: H₂NCH₂C₆H₄CO₂H
• CAS Number: 56-91-7
• Molecular Weight: 151.16
• Beilstein: 1100606
• EC Number: 200-297-9
• MDL number: MFCD00010203
• UNSPSC Code: 12352106
• eCl@ss: 32160406
• PubChem Substance ID: 24857129
• NACRES: NA.22

Properties

• Product Name: 4-(Aminomethyl)benzoic acid, 97%
• Quality Level: 200
• Assay: 97%
• form: powder
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: ≥300 °C (lit.)
• application(s): peptide synthesis
• SMILES string: NCc1ccc(cc1)C(O)=O
• InChI: 1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
• InChI key: QCTBMLYLENLHLA-UHFFFAOYSA-N

Description

Application

4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:

• Cobalt carboxy phosphonates.
• Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
• Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
• A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.

Other Notes

4-(Aminomethyl)benzoic acid is also an antihemorrhagic agent, which is used for the treatment of internal haemorrhage.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves