399337

Benzamide

purified by sublimation, ≥99.5%

• Synonym(s): Benzoic acid amide
• Linear Formula: C₆H₅CONH₂
• CAS Number: 55-21-0
• Molecular Weight: 121.14
• Beilstein: 385876
• EC Number: 200-227-7
• MDL number: MFCD00007968
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864807
• NACRES: NA.22

Properties

• Assay: ≥99.5%
• form: powder
• purified by: sublimation
• mp: 125-128 °C (lit.)
• solubility: ethanol: soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow
• functional group: amide; phenyl
• SMILES string: NC(=O)c1ccccc1
• InChI: 1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
• InChI key: KXDAEFPNCMNJSK-UHFFFAOYSA-N
• Gene Information: human ... PARP1(142)

Description

General description

Benzamide (Benzoic acid amide, BA) is an amide of benzoic acid. BA on crystallization in benzene (solvent) affords crystals suitable for X-ray analysis. Crystal structure studies suggest that its crystals are monoclinic having space group P2₁/c. Kinetics and mechanism of its reaction with hydrogen peroxide have been proposed.

Application

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. Benzamide was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Biochem/physiol Actions

Inhibits poly(ADP-ribose) polymerase (PARP).

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H341
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Muta. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 356.0 °F - closed cup
• Flash Point(C): 180 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves