637637

3-Chloro-6-methylpyridazine

97%

• Empirical Formula (Hill Notation): C₅H₅ClN₂
• CAS Number: 1121-79-5
• Molecular Weight: 128.56
• MDL number: MFCD00052905
• UNSPSC Code: 12352100
• PubChem Substance ID: 24882876
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 58-62 °C
• functional group: chloro
• SMILES string: Cc1ccc(Cl)nn1
• InChI: 1S/C5H5ClN2/c1-4-2-3-5(6)8-7-4/h2-3H,1H3
• InChI key: PRORLQAJNJMGAR-UHFFFAOYSA-N

Description

Application

3-Chloro-6-methyl pyridazine can undergo nickel catalyzed cross coupling reaction with aromatic and heteroaromatic halides, to give the corresponding substituted aryl- and heteroaryl pyridazines. It can also be used in the synthesis of a p38MAP kinase inhibitor with therapeutic potential in the treatment of autoimmune and inflammatory diseases.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H317,H318
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves