D8802

Dextran solution from Leuconostoc mesenteroides

20 % (w/w) (Autoclaved)

• Synonym(s): repeating α-linked D-glucopyranosyl units, synthesized from sucrose by Leuconostoc mesenteroides
• CAS Number: 9004-54-0
• MDL number: MFCD00130935
• UNSPSC Code: 12352201
• NACRES: NA.75

Properties

• form: liquid
• Quality Level: 200
• mol wt: average mol wt ~500,000
• concentration: 20 % (w/w) (Autoclaved)
• technique(s): titration: suitable
• color: colorless
• density: 1.00-1.20 g/mL
• application(s): hematology; histology
• storage temp.: 2-8°C
• SMILES string: O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
• InChI: 1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
• InChI key: FZWBNHMXJMCXLU-UHFFFAOYSA-N

Description

General description

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, with a linear backbone of α-linked D-glucopyranosyl repeating units. Dextrans are found as bacterial extracellular polysaccharides. They are synthesized from sucrose by Leuconostoc mesenteroides. Bacteria employ dextran in biofilm formation or as a protective coating to evade host phagocytes in the case of pathogenic bacteria.

Application

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants, and physical structure components.Dextran from Leuconostoc mesenteroides (Mw: 670,000) may be used as an analytical standard to calibrate the column for gel permeation chromatography (GPC). It has been used to sediment erythrocytes from blood along with 0.9% sodium chloride.

Use of dextrans as long and hydrophilic spacer arms to improve the performance of immobilized proteins acting on macromolecules.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable