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D8802

Sigma-Aldrich

Dextran solution from Leuconostoc mesenteroides

20 % (w/w) (Autoclaved)

Synonym(s):

repeating α-linked D-glucopyranosyl units, synthesized from sucrose by Leuconostoc mesenteroides

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.75

form

liquid

Quality Level

mol wt

average mol wt ~500,000

concentration

20 % (w/w) (Autoclaved)

technique(s)

titration: suitable

color

colorless

density

1.00-1.20 g/mL

application(s)

hematology
histology

storage temp.

2-8°C

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

General description

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, with a linear backbone of α-linked D-glucopyranosyl repeating units. Dextrans are found as bacterial extracellular polysaccharides. They are synthesized from sucrose by Leuconostoc mesenteroides. Bacteria employ dextran in biofilm formation or as a protective coating to evade host phagocytes in the case of pathogenic bacteria.

Application

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants, and physical structure components.Dextran from Leuconostoc mesenteroides (Mw: 670,000) may be used as an analytical standard to calibrate the column for gel permeation chromatography (GPC). It has been used to sediment erythrocytes from blood along with 0.9% sodium chloride.

Use of dextrans as long and hydrophilic spacer arms to improve the performance of immobilized proteins acting on macromolecules.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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