404R-1

C4d (SP91) Rabbit Monoclonal Antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: SP91, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (404R-14); vial of 0.5 mL concentrate (404R-15); bottle of 1.0 mL predilute (404R-17); vial of 1.0 mL concentrate (404R-16); bottle of 7.0 mL predilute (404R-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• isotype: IgG
• control: lymph node, tonsil
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic, membranous
• Gene Information: human ... C4B(721)

Description

General description

Acute humoral rejection is mediated by antibodies to the donor endothelium that activates the classical complement pathway. This leads to a number of split products of complement proteins. C4d is a fragment of C4 complement released during activation of the classic complement pathway by the antigen-antibody complex. C4d deposits in peritubular capillaries and is regarded as an indirect sign of an antibody response. C4d can be a useful tool for indicating acute renal allograft rejection.

Quality

IVD

IVD

IVD

RUO

Linkage

C4d Positive Control Slides, Product No. 404S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable