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About This Item

Empirical Formula (Hill Notation):
C22H22N6O7S2 · xH2O
CAS Number:
120618-65-7
Molecular Weight:
546.58 (anhydrous basis)
MDL number:
MFCD00153936
UNSPSC Code:
51284108
PubChem Substance ID:
24892644
NACRES:
NA.85
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Quality Level

200

Assay

90.0-105.0%

form

powder or crystals

contains

~10% sodium carbonate as stabilizer

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c4csc(N)n4)C(O)=O

InChI

1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1

InChI key

NMVPEQXCMGEDNH-TZVUEUGBSA-N

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Related Categories

General description

Broad spectrum antibiotic; third generation cephalosporin
Chemical structure: ß-lactam

Application

Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.
Used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis.

Biochem/physiol Actions

Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H319,H334

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD4353V
049M4806V
20140401
019M4859V
029M4820V

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