L0544
Monoclonal Anti-Leukemia Inhibitory Factor antibody produced in rat
clone 139124, purified immunoglobulin, lyophilized powder
Synonym(s):
Anti-Lif
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About This Item
UNSPSC Code:
51111800
NACRES:
NA.41
biological source
rat
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
139124, monoclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
western blot: 1-2 μg/mL
isotype
IgG2b
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Lif(16878)
Immunogen
purified, E. coli-derived recombinant mouse leukemia inhibitory factor.
Biochem/physiol Actions
Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Product No.
Description
Pricing
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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