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About This Item
Empirical Formula (Hill Notation):
C13H11NO5
CAS Number:
Molecular Weight:
261.23
Beilstein:
620635
EC Number:
MDL number:
UNSPSC Code:
51282935
PubChem Substance ID:
NACRES:
NA.85
Quality Level
solubility
0.5 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Mode of action
DNA synthesis | interferes
enzyme | inhibits
storage temp.
2-8°C
SMILES string
CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12
InChI
1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
InChI key
KYGZCKSPAKDVKC-UHFFFAOYSA-N
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Related Categories
General description
Chemical structure: quinolone
Application
Oxolinic acid is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. Oxolinic acid is added to culture medium for the isolation of Gardnerella vaginalis.
Biochem/physiol Actions
Oxolinic acid is a quinolone antibiotic. It is a DNA-gyrase (topoisomerase II) inhibitor used for studies on DNA winding and coiling and acts as a dopamine reuptake inhibitor for studies on dopaminergic neurotransmission processes.
Other Notes
5g,25g
Keep container tightly closed in a dry and well-ventilated place.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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