P0359
Palmitoylethanolamide
≥98% (HPLC), powder, cannabinoid receptor agonist
Synonym(s):
N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
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About This Item
Empirical Formula (Hill Notation):
C18H37NO2
CAS Number:
Molecular Weight:
299.49
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
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Product Name
Palmitoylethanolamide,
form
powder
Quality Level
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCCCC(=O)NCCO
InChI
1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChI key
HXYVTAGFYLMHSO-UHFFFAOYSA-N
Gene Information
human ... CNR1(1268), CNR2(1269)
rat ... Faah(29347)
Related Categories
Application
Palmitoylethanolamide has been used as a reference standard in mass spectrometry (MS/MS).
Biochem/physiol Actions
Palmitoylethanolamide (PEA) is a natural fatty acid amide of ethanolamine and palmitic acid. It is found in soybeans, egg yolk, and many other food sources. PEA is an endogenous cannabinoid receptor agonist. It is a peroxisome proliferator-activated receptor α (PPAR-α) ligand. PEA possesses anti-inflammatory, anti-allergic, neuroprotective, and analgesic activities. It belongs to the class of lipid mediators and the N-acylethanolamine family. PEA blocks the release of pro-inflammatory mediators from activated mast cells and prevents the recruitment of activated mast cells at the site of nerve injury.
Linkage
Structural analog of anandamide.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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