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Key Documents

R4877

Sigma-Aldrich

Rennin from calf stomach

≥20 units/mg protein

Synonym(s):

Chymosin

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About This Item

CAS Number:
EC Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54

form

lyophilized powder

Quality Level

specific activity

≥20 units/mg protein

purified by

crystallization

composition

Protein, ≥40%

storage temp.

−20°C

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Application

Rennin, also known as chymosin, is a milkclotting acid proteinase produced in the stomach of a calf. It is used in cheesemaking and to study neonatal gastric digestion .

Biochem/physiol Actions

Rennin, a 323 amino acid chain, is secreted as an inactive precursor which is then converted into an active enzyme through limited proteolysis. It cleaves the peptide bond between phenylalanine and methionine in K-Casein.

Packaging

Package size based on protein content

Unit Definition

One unit will coagulate 10 mL of milk per min at 30 °C.

Physical form

Lyophilized powder containing sodium chloride

Analysis Note

Protein determined by biuret.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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