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About This Item
Empirical Formula (Hill Notation):
C9H12N2O6
CAS Number:
Molecular Weight:
244.20
Beilstein:
754902
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.75
biological source
synthetic (organic)
product line
BioReagent
Assay
≥99%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
163-167 °C (lit.)
solubility
H2O: 50 mg/mL
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
Gene Information
mouse ... Uck1(22245)
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General description
Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is a substrate for nucleotide synthesis in living organisms by de- novo and salvage pathways.
Application
Uridine has been used:
- as an inhibitor of schwann cell proliferation in rat dorsal root ganglia (DRG) neurons culture
- as a medium supplement for epiblasts culture
- as a component of 5-fluoro-2′-deoxyuridine stock solution used for neuronal culture
Biochem/physiol Actions
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like, treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine induces insulin resistance.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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