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WH0003814M5

Sigma-Aldrich

Monoclonal Anti-KISS1 antibody produced in mouse

clone 1F7, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-KiSS-1 metastasis-suppressor, Anti-KiSS1, Anti-MGC39258

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1F7, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

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Show Differences

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This Item
I14150426393Y0002263
Diisobutylamine 99%

135186

Diisobutylamine

Isobutylamine 99%

I14150

Isobutylamine

1-tert-Butyl-3-ethylcarbodiimide 99%

426393

1-tert-Butyl-3-ethylcarbodiimide

vibrant-m

Y0002263

N-Nitroso-diisopropylamine

assay

99%

assay

99%

assay

99%

assay

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

bp

137-139 °C (lit.)

bp

64-71 °C (lit.)

bp

137-139 °C (lit.)

bp

-

refractive index

n20/D 1.4081 (lit.)

refractive index

n20/D 1.397 (lit.)

refractive index

n20/D 1.432 (lit.)

refractive index

-

form

liquid

form

liquid

form

liquid

form

-

mp

−77 °C (lit.)

mp

−85 °C (lit.)

mp

-

mp

-

General description

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. (provided by RefSeq)

Immunogen

KISS1 (NP_002247, 46 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRGWGAGAGQ

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    11018-1F4
    11018-1F7
    08078-1F7
    06356-1F7

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