On-line HPLC Integration for Bioprocessing Control

WEBINAR

High-performance liquid chromatography (HPLC) is a proven tool for the analysis of critical process parameters (CPP) and critical quality attributes (CQA) of biotherapeutics. Historically, HPLC has been performed off-line – a process that can take days or weeks to complete. By moving HPLC to the manufacturing floor as an on-line Process Analytical Technology (PAT) tool, relevant data can be accessed in a matter of minutes. In this webinar, we highlight an initial use case, demonstrating the utility of on-line HPLC to monitor and control antibody aggregation levels in bioprocessing. The implementation of PAT enables continuous manufacturing and empowers industry progress towards Bioprocessing 4.0.

In this webinar, you will learn:

• How Process Analytical Technology (PAT) tools can facilitate progress towards Biopharma 4.0 and real-time release
• How on-line HPLC can be implemented in a bioprocessing environment
• The application of on-line HPLC to monitor and control critical quality attributes in bioprocessing