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Merck
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About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
Molecular Weight:
30.03 (as monomer)
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
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vapor density

1.03 (vs air)

Quality Level

vapor pressure

<1.45 mmHg ( 25 °C)

Assay

95%

form

powder

autoignition temp.

572 °F

expl. lim.

73 %

mp

120-170 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

Paraformaldehyde is also referred as polyoxymethylene. It participates as an external CO source in the synthesis of aromatic aldehydes and esters.

Application

Paraformaldehyde can be used as a:
  • Methylene building block in the Mannich reaction with primary amines and alkynes to synthesize propargyl amines.
  • Hydroxymethylation reagent to synthesize homoallylic alcohols by reacting with 1,1-disubstituted allenes.
  • Formylation reagent in the Ir-catalyzed N-formylation of amines to synthesize formamides.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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