TrypZean^® solution, 1× is formulated with TrypZean, recombinant bovine trypsin expressed in corn and manufactured utilizing ProdiGene′s proprietary transgenic plant protein expression system. This product is optimized for cell dissociation in both serum-free and serum-supplemented adherent cell cultures.

TrypZean^® Solution, 1× has been used:

• for the suspension of pellet during DNA extraction
• digestion of cells to single-cell suspension for pharmacotyping of 2D cells
• as recombinant trypsin to induce cell division of Vero cells sub cultivated in IPT-AF medium

TrypZean^® Solution provides the following features and benefits:

• Animal component-free – eliminates the risk of viruses, BSE, or other potential adventitious agents
• TrypZean is recombinant trypsin – using the same enzyme (with the same kinetics) for cell detachment means minimal protocol changes
• Enzyme inhibition – soybean trypsin inhibitor and other inhibitors work the same with TrypZean as they do with native trypsins (weight-to-weight basis)
• High purity – TrypZean provides increased specificity and eliminates contaminating activities found in lower purity enzymes
• Convenience – TrypZean solution is a sterile-filtered solution formulated at the optimal concentration to dissociate adherent cell lines

Trypzean is a registered trademark of ProdiGene, Inc.