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ACACA

acetyl-CoA carboxylase alpha

Synonyms:
ACAC, ACACAD, ACC, ACC1, ACCA
Species:
UniProtKB ID:
Gene ID:
  • Human(31) Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(107476) acetyl-Coenzyme A carboxylase alpha
  • Rat(60581) acetyl-CoA carboxylase alpha
  • Zebrafish(559403) acetyl-Coenzyme A carboxylase alpha
  • dog(491130) acetyl-CoA carboxylase alpha
  • cow(281590) acetyl-CoA carboxylase alpha
  • Horse(100071472) acetyl-CoA carboxylase alpha
  • domestic cat(101083046) acetyl-CoA carboxylase alpha
  • chicken(396504) acetyl-CoA carboxylase alpha
  • Goat(100861224) acetyl-CoA carboxylase alpha
  • Domestic Rabbit(100355970) acetyl-CoA carboxylase alpha
  • sheep(443186) acetyl-CoA carboxylase alpha
  • domestic guinea pig(100733410) acetyl-CoA carboxylase alpha
  • naked mole-rat(101706028) acetyl-CoA carboxylase alpha

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Acetyl-CoA Carboxylase (pSer80) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-ACC1 (pSer80) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-ACACA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ACC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Phospho Acetyl CoA Carboxylase (Ser79) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM270, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Acetyl-CoA Carboxylase 1 human, recombinant, expressed in Sf9 cells,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACACA (2),
Species
human
MISSION® esiRNA, targeting mouse Acaca,
Species
mouse
MISSION® esiRNA, targeting human ACACA (1),
Species
human