POLK
polymerase (DNA directed) kappa
Synonyms:
DINB1, DINP, POLQ
Species:
Human POLK (51426), Mouse Polk (27015), Rat Polk (171525), naked mole-rat Polk (101718580), Domestic Rabbit POLK (100352218), domestic guinea pig Polk (100726233), cow POLK (541218), sheep POLK (101109360), Zebrafish polk (562749), chicken POLK (374003) ...More
UniProtKB ID:
Gene ID:
- Human(51426) Summary: External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]
- Mouse(27015) polymerase (DNA directed), kappa
- Rat(171525) polymerase (DNA directed) kappa
- naked mole-rat(101718580) polymerase (DNA directed) kappa
- Domestic Rabbit(100352218) polymerase (DNA directed) kappa
- domestic guinea pig(100726233) polymerase (DNA directed) kappa
- cow(541218) polymerase (DNA directed) kappa
- sheep(101109360) polymerase (DNA directed) kappa
- Zebrafish(562749) polymerase (DNA directed) kappa
- chicken(374003) polymerase (DNA directed) kappa
- dog(479180) polymerase (DNA directed) kappa
- domestic cat(101099613) polymerase (DNA directed) kappa
- Horse(100065534) polymerase (DNA directed) kappa
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-POLK antibody produced in mouse, clone 4F12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-POLK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-POLK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, mouse, pig, rat
Application
western blot
Anti-POLK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rat
Application
western blot
Monoclonal Anti-POLK antibody produced in mouse, clone 6F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot