PRMT6
protein arginine methyltransferase 6
Synonyms:
HRMT1L6
Species:
Human PRMT6 (55170), Mouse Prmt6 (99890), Rat Prmt6 (295384), Thale Cress PRMT6 (821541), domestic cat PRMT6 (101093626), dog PRMT6 (490133), Zebrafish prmt6 (448867), naked mole-rat Prmt6 (101715374), domestic guinea pig Prmt6 (100725259), cow PRMT6 (540228)
UniProtKB ID:
Gene ID:
- Human(55170) Summary: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
- Mouse(99890) protein arginine N-methyltransferase 6
- Rat(295384) protein arginine methyltransferase 6
- Thale Cress(821541) protein arginine N-methyltransferase 6
- domestic cat(101093626) protein arginine methyltransferase 6
- dog(490133) protein arginine methyltransferase 6
- Zebrafish(448867) protein arginine methyltransferase 6
- naked mole-rat(101715374) protein arginine methyltransferase 6
- domestic guinea pig(100725259) protein arginine methyltransferase 6
- cow(540228) protein arginine methyltransferase 6
- sheep(101119859) protein arginine methyltransferase 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRMT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PRMT6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PRMT6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
ChIP
western blot
western blot
Anti- PRMT6 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-PRMT6 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, pig, rat
Application
ELISA
western blot
western blot