B9385

Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride

• Empirical Formula (Hill Notation): C₃₁H₄₅N₇O₇
• CAS Number: 70375-24-5
• Molecular Weight: 627.73
• MDL number: MFCD00058181
• UNSPSC Code: 12352204
• PubChem Substance ID: 24892134
• NACRES: NA.32

Properties

• assay: ≥98% (TLC)
• Quality Level: 200
• form: powder
• solubility: water: 20 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Cl.CC(C)C(NC(=O)OC(C)(C)C)C(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
• InChI: 1S/C31H45N7O7.ClH/c1-17(2)25(37-30(43)45-31(4,5)6)28(42)38-14-8-10-22(38)27(41)36-21(9-7-13-34-29(32)33)26(40)35-19-11-12-20-18(3)15-24(39)44-23(20)16-19;/h11-12,15-17,21-22,25H,7-10,13-14H2,1-6H3,(H,35,40)(H,36,41)(H,37,43)(H4,32,33,34);1H
• InChI key: ROQGJTZGLVLVIN-UHFFFAOYSA-N

Description

General description

Boc-Val-Pro-Arg-AMC serves as a synthetic substrate for human kallikrein 8.

Application

Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride has been used:

• as a fluorogenic substrate for thrombin in inhibitory assay with salivary protein cE5
• as a fluorogenic substrate for thrombin in inhibitory assay with recombinant E. nipponicum serpin
• as a substrate in proteinase assay with hemolymph protein

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

A fluorogenic substrate for thrombin.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)