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About This Item

Empirical Formula (Hill Notation):
C14H27N3O8
CAS Number:
Molecular Weight:
365.38
UNSPSC Code:
12352106
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assay

95%

form

(Liquid or Semi-Solid or Paste or Solid)

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

functional group

azide
carboxylic acid

storage temp.

2-8°C

SMILES string

OC(COCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Application

This heterobifunctional, PEGylated crosslinker 20-Azido-3,6,9,12,15,18-hexaoxaicosanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG6-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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