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About This Item

Empirical Formula (Hill Notation):
C21H42O7PNa
CAS Number:
Molecular Weight:
460.52
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1-stearoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)

assay

>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)

form

powder

packaging

pkg of 1 × 25 mg (857128P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI key

YJQFVAZHPIBPHN-VEIFNGETSA-M

General description

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells. 18:0 Lyso PA has stearic acid at sn-1 and a hydroxyl group at sn-2 position.

Application

18:0 Lyso PA is suitable for use:
  • to determine the extraction recovery of LPA at neutral pH and acidic pH by chromatographic method
  • to use as internal standard to study the role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
  • to investigate its effects on clathrin?dependent endocytosis

Biochem/physiol Actions

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

Packaging

5 mL Amber Glass Screw Cap Vial (857128P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


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