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ABN192

Sigma-Aldrich

Anti-ZFP36L1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B

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1 EA
CA$5,340.00

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CA$5,340.00

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biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

bovine (based on 100% sequence homology), canine (based on 100% sequence homology), horse (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_001231627

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Astec® Chirobiotic® R Chiral HPLC Column 5 μm particle size, L × I.D. 25 cm × 2.1 mm

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Astec® Chirobiotic® R Chiral HPLC Column

Astec® Chirobiotic® R Chiral HPLC Column 5 μm particle size, L × I.D. 15 cm × 2.1 mm

13019AST

Astec® Chirobiotic® R Chiral HPLC Column

Astec® Chirobiotic® R Chiral HPLC Column 5 μm particle size, L × I.D. 10 cm × 4.6 mm

13022AST

Astec® Chirobiotic® R Chiral HPLC Column

Astec® Chirobiotic® R Chiral HPLC Column 5 μm particle size, L × I.D. 15 cm × 4.6 mm

13023AST

Astec® Chirobiotic® R Chiral HPLC Column

matrix active group

ristocetin A glycopeptide phase

matrix active group

ristocetin A glycopeptide phase

matrix active group

ristocetin A glycopeptide phase

matrix active group

ristocetin A glycopeptide phase

separation technique

chiral

separation technique

chiral

separation technique

chiral

separation technique

chiral

L × I.D.

25 cm × 2.1 mm

L × I.D.

15 cm × 2.1 mm

L × I.D.

10 cm × 4.6 mm

L × I.D.

15 cm × 4.6 mm

particle size

5 μm

particle size

5 μm

particle size

5 μm

particle size

5 μm

matrix

high-purity silica gel particle platform, fully porous particle

matrix

high-purity silica gel particle platform, fully porous particle

matrix

high-purity silica gel particle platform, fully porous particle

matrix

high-purity silica gel particle platform, fully porous particle

product line

Astec®

product line

Astec®

product line

Astec®

product line

Astec®

General description

As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.

Specificity

This antibody recognizes the C-terminus of ZFP36L1.

Immunogen

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.

Application

Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Quality

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.

Target description

~38 kDa observed

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HeLa cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
B DeCruze et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 11(4), 252-254 (1999-09-04)
Poor prognosis (poorly differentiated and/or deep myometrial invasion) Stage I endometrial cancer can have a relapse rate as high as 50%. Traditionally, most clinical oncologists treat these patients with external beam radiotherapy after surgery but there is no evidence to
Diane E Halliwell et al.
Scientific data, 4, 170084-170084 (2017-07-12)
Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal
Sébastien Canneaux et al.
The journal of physical chemistry. A, 114(34), 9270-9288 (2010-08-03)
The rate constants of the reactions of iodine atoms with H(2), H(2)O, HI, and OH have been estimated using 39, 21, 13, and 39 different levels of theory, respectively, and have been compared to the available literature values over the
Ting Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1002, 218-227 (2015-09-06)
The chiral inversion has been a concerned issue during the research and development of a chiral drug. In this study, a sensitive chiral liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of salbutamol enantiomers in human plasma and
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