Methylcytosine dioxygenase TET3 (TET3) is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET3 is involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization. TET3 is expressed in colon, muscle, adrenal gland, and peripheral blood lymphocytes. It is also expressed in fetal brain but not adult brain.

KLH-conjugated linear peptide corresponding to human TET3.

Anti-TET3 Antibody is a highly specific rabbit polyclonal antibody, that targets Methylcytosine dioxygenase TET3 & has been tested in western blotting.

Research Category
Signaling

Research Sub Category
Developmental Signaling

Evaluated by Western Blotting/Peptide Inhibition Assay in SK-N-SH cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected TET3 in 15 µg of SK-N-SH cell lysate.

~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 3 isoforms at ~77 kDa, ~167 kDa, and ~180 kDa

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
SK-N-SH cell lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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