The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. KLHL1 contains one BTB (POZ) domain and six Klech repoeats. KLHL1 may play an important role in organizing the actin cytoskeleton of the brain cells. Mutations associated with KLHL1 are inplicated in spinocerebellar ataxia type 8 (SCA8).

KLH-conjugated linear peptide corresponding to human KLHL1.

Detect Kelch-like 1 using this rabbit polyclonal antibody, Anti-KLHL1 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected KLHL1 in rat brain tissue.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 4 µg/mL of this antibody detected KLHL1 in 15 µg/mL of human brain tissue lysate.

~100 kDa observed

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Human brain tissue lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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