Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.

Antibody recognizes integrin β1.

Research Category
Cell Structure

Research Sub Category
Integrins

This Milli-Mark Anti-Integrin β1 (CD29)-FITC conjugate Antibody, clone MB1.2 is validated for use in FC for the detection of Integrin β1 (CD29) conjugate.

Evaluated by flow cytometry using NIH/3T3

88 kDa Calculated

Protein A purified

Purified rat monoclonal IgG2a conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Control
NIH/3T3 cells

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