description
GPCR Class A
protein target CCR2B
Quality Level
technique(s)
radioligand binding assay (RLBA): suitable
UniProt accession no.
Gene Information
human ... CCR2(729230)
General description
FUNCTION: SwissProt: P41597 # Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
SIZE: 374 amino acids; 41915 Da
SUBUNIT: Binds to HIV-1 Tat.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
PTM: N-glycosylated.
SIMILARITY: SwissProt: P41597 ## Belongs to the G-protein coupled receptor 1 family.
SIZE: 374 amino acids; 41915 Da
SUBUNIT: Binds to HIV-1 Tat.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
PTM: N-glycosylated.
SIMILARITY: SwissProt: P41597 ## Belongs to the G-protein coupled receptor 1 family.
Physical form
Liquid in packaging buffer: 50 mM Tris pH 7.4, 10% glycerol and 1% BSA with no preservatives.
Packaging method: Membrane protein was adjusted to 1 mg/ml in 1 ml packaging buffer, rapidly frozen, and stored at -80°C.
Packaging method: Membrane protein was adjusted to 1 mg/ml in 1 ml packaging buffer, rapidly frozen, and stored at -80°C.
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Certificates of Analysis (COA)
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