Skip to Content
MilliporeSigma
All Photos(4)

Key Documents

View All Documentation

A5000

Sigma-Aldrich

Acetaminophen

meets USP testing specifications, 98.0-102.0%, powder

Synonym(s):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Linear Formula:
CH3CONHC6H4OH
CAS Number:
103-90-2
Molecular Weight:
151.16
Beilstein/REAXYS Number:
2208089
MDL number:
MFCD00002328
UNSPSC Code:
12352111
PubChem Substance ID:
24890930
NACRES:
NA.25
Pricing and availability is not currently available.

agency

USP/NF
meets USP testing specifications

Quality Level

200

assay

98.0-102.0%

form

powder

mp

168-172 °C (lit.)

solubility

DMSO: 5 M
ethanol: 50 mg/mL
H2O: very slightly soluble

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
X104095660PHR1312
o-Xylene puriss. p.a., ≥99.0% (GC)

95662

o-Xylene

o-Xylene reagent grade, ≥98.0%

X1040

o-Xylene

o-Xylene analytical standard

95660

o-Xylene

o-Xylene Pharmaceutical Secondary Standard; Certified Reference Material

PHR1312

o-Xylene

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

300

grade

puriss. p.a.

grade

-

grade

-

grade

-

solubility

water: partially soluble 0.1705 g/L at 25 °C

solubility

-

solubility

-

solubility

-

form

liquid

form

liquid

form

-

form

-

density

0.879 g/mL at 20 °C (lit.)

density

0.879 g/mL at 20 °C (lit.)

density

0.879 g/mL at 20 °C (lit.)

density

0.879 g/mL at 20 °C (lit.)

Application

Analgesic.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCQ8545
    MKCN0690
    MKCL1130
    MKCJ5427
    MKCD6375

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Mohammad A Rahman et al.
    Scientific reports, 9(1), 6571-6571 (2019-04-27)
    Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytochrome P450
    S M de Morais et al.
    Gastroenterology, 102(2), 577-586 (1992-02-01)
    Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
    Edward Munsterhjelm et al.
    Anesthesiology, 103(4), 712-717 (2005-09-30)
    Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
    Mitchell R McGill et al.
    Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
    Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
    Garry G Graham et al.
    Drug safety, 28(3), 227-240 (2005-03-01)
    The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service