PHR1036

Pyridoxine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 3-Hydroxy-4,5-bis (hydroxymethyl)-2-picoline hydrochloride, Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B₆ hydrochloride
• Empirical Formula (Hill Notation): C₈H₁₁NO₃ · HCl
• CAS Number: 58-56-0
• Molecular Weight: 205.64
• Beilstein/REAXYS Number: 3632435
• EC Number: 200-386-2
• MDL number: MFCD00012807
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823066
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to BP 458; traceable to Ph. Eur. P4100000; traceable to USP 1587001
• API family: pyridoxine
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 214-215 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C

Description

General description

Pyridoxine hydrochloride is a water soluble vitamin, widely used for the prevention of peripheral neuropathy and central nervous system effects associated with therapy involving isoniazid. It is highly required for the formation of hemoglobin and is also mainly involved in carbohydrate, fat and amino acid metabolism.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Pyridoxine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography and spectrophotometric techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3720 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable