238074

Ammonium acetate

ACS reagent, ≥97%

• Linear Formula: CH₃CO₂NH₄
• CAS Number: 631-61-8
• Molecular Weight: 77.08
• Beilstein/REAXYS Number: 4186741
• EC Number: 211-162-9
• MDL number: MFCD00013066
• UNSPSC Code: 12352300
• eCl@ss: 39021908
• PubChem Substance ID: 329752506
• NACRES: NA.21
• Assay: ≥97%
• Grade: ACS reagent
• Form: powder; solid

Properties

• grade: ACS reagent
• vapor pressure: <0.001 hPa
• assay: ≥97%
• form: powder; solid
• impurities: ≤0.005% insolubles
• ign. residue: ≤0.01%
• pH: 6.7-7.3 (25 °C, 5%)
• mp: 110-112 °C (dec.) (lit.)
• anion traces: chloride (Cl^-): ≤5 ppm; nitrate (NO₃^-): ≤0.001%; sulfate (SO₄^2-): ≤0.001%
• cation traces: Fe: ≤5 ppm; heavy metals: ≤5 ppm

Description

General description

Ammonium acetate (NH₄CH₃CO₂, NH₄OAc) is a water-soluble, hygroscopic ammonium salt. It is an eco-friendly and inexpensive compound that can be prepared by reacting glacial acetic acid with ammonia or ammonium carbonate. It is used as a catalyst as well as a source of ammonia in organic synthesis.

Application

Ammonium acetate can be used as a reactant as well as a catalyst in the synthesis of:      

• 1,3-oxazine derivatives by three-component condensation reaction with 2-naphthol and aromatic aldehydes.      
• Symmetrical terpyridine derivatives by treating with aromatic aldehydes and ethyl cyanoacetate.      
• Isoquinolines, furopyridines, and thienopyridines via Pd-catalyzed sequential coupling-imination-annulation reactions of ortho-bromoarylaldehydes and terminal alkynes.

It can also be used as a nitrogen source to synthesize benzoxazole derivatives via multicomponent condensation reaction with catechols, and various aldehydes in the presence of Fe(III)−salen complex as a catalyst.

Features and Benefits

NH₄OAc is an eco-friendly, shelf-stable, and safe reagent.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable