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Key Documents

M6292

Sigma-Aldrich

Macrophage Inflammatory Protein-1α human

≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

MIP-1α

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About This Item

MDL number:
UNSPSC Code:
51111800

biological source

human

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE and N-terminal analysis)

form

lyophilized powder

potency

2-25 ng/mL EC50

mol wt

Mw 7500 Da

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... CCL3(6348)

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Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to chemoattract cultured human monocytes or mouse BaF/3 cells transfected with human CCR5.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ping Shi et al.
Oncology reports, 34(3), 1319-1326 (2015-07-03)
In recent years, astrocyte elevated gene-1 (AEG-1) has been reported as a key mediator that is involved in the epithelial-to-mesenchymal transition (EMT) process. However, the mechanisms underlying CCL3/CCR5-AEG-1 pathway-mediated EMT in cardiac myxoma (CM) has not been well featured till

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