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About This Item
Linear Formula:
HO2C(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
161.16
Beilstein/REAXYS Number:
1724347
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32
form
powder
Quality Level
mp
208-210 °C (lit.)
SMILES string
N[C@H](CCCC(O)=O)C(O)=O
InChI
1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
InChI key
OYIFNHCXNCRBQI-SCSAIBSYSA-N
Gene Information
rat ... Grin2a(24409), Grm1(24414), Grm2(24415), Grm6(24419)
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Application
D-2-Aminoadipic acid has been used as an inhibitor of glutamine synthetase in spontaneously immortalized human cell line MIO-M1.
Biochem/physiol Actions
D-2-Aminoadipic acid is a glutamate analog. It acts as an inhibitor of glutamate synthetase. D-2-Aminoadipic acid exhibits gliotoxicity towards mitotic astrocytes.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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