biological source
human
Quality Level
recombinant
expressed in NS.1 cells
assay
>98% (SDS-PAGE)
form
buffered aqueous solution
mol wt
98 kDa
packaging
pkg of 10 μg
impurities
endotoxin, tested
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL10(3586)
General description
The gene IL-10 (interleukin-10) is mapped to human chromosome 1q31-32. It is secreted by monocytes and lymphocytes.
Biochem/physiol Actions
IL-10 (interleukin-10) is an anti-inflammatory cytokine. High levels of IL-10 are present in late syphilis. It suppresses Th1 (T helper) cytokines. IL-10 also controls the differentiation and proliferation of T cells, B cells, natural killer cells, antigen-presenting cells and mast cells.
Possesses the biological function of the IL-10 moiety and a prolonged circulating half-life determined by the Fc domain.
Other Notes
Dimeric fusion protein consisting of human IL-10 fused to mutant human IgG1 Fc.
Physical form
Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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