O0886

Olomoucine

≥98% (HPLC)

• Synonym(s): 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine
• Empirical Formula (Hill Notation): C₁₅H₁₈N₆O
• CAS Number: 101622-51-9
• Molecular Weight: 298.34
• MDL number: MFCD00189360
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278053
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: 20 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12
• InChI: 1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20)
• InChI key: GTVPOLSIJWJJNY-UHFFFAOYSA-N
• Gene Information: human ... CDC2(983), CDK2(1017), CDK3(1018), CDK4(1019), CDK5(1020), CDK6(1021), CDK7(1022), CDK8(1024), CDK9(1025), CDKN1A(1026), CDKN1B(1027), CDKN1C(1028), CDKN2A(1029), CDKN2B(1030), CDKN2C(1031), CDKN2D(1032), CDKN3(1033) ; rat ... Prkca(24680)

Description

Biochem/physiol Actions

Olomoucine is a purine derivative which inhibits cyclin-dependent kinases and induces G arrest.

Features and Benefits

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)