Skip to Content
Merck

Skip To

S4441

Sigma-Aldrich

D,L-Sulforaphane

≥90% (HPLC), liquid, phase II detoxification enzymes inducer

Synonym(s):

1-Isothiocyanato-4-(methylsulfinyl)-butane

Sign Into View Organizational & Contract Pricing

Select a Size

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C6H11NOS2
CAS Number:
Molecular Weight:
177.29
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

DL-Sulforaphane, ≥90% (HPLC), synthetic, liquid

biological source

synthetic

Quality Level

assay

≥90% (HPLC)

form

liquid

solubility

DMSO: soluble 40 mg/mL
H2O: insoluble

compatibility

for use with ABI 7500

shipped in

dry ice

storage temp.

−20°C

SMILES string

CS(=O)CCCCN=C=S

Related Categories

Application

LNCaP prostate cancer cells were treated with DL-Sulforaphane to study the effect on androgen receptor. Effects on malathion toxicity was studied in rats by treating them with DL-Sulforaphane.

Biochem/physiol Actions

Selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service