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Key Documents

SAB1405692

Sigma-Aldrich

Anti-CYP11A1 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

CYP11A, P450SCC

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~60.1 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

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grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

application(s)

pharmaceutical

application(s)

pharmaceutical

application(s)

pharmaceutical

application(s)

pharmaceutical

agency

traceable to USP 1457888

agency

traceable to USP 1367606

agency

traceable to USP 1133966

agency

traceable to USP 1457877

CofA

current certificate can be downloaded

CofA

current certificate can be downloaded

CofA

current certificate can be downloaded

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

packaging

pkg of 50 mg

packaging

pkg of 100 mg

packaging

pkg of 150 mg

storage temp.

-10 to -25°C

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

General description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. (provided by RefSeq)

Immunogen

CYP11A1 (AAH32329.1, 1 a.a. ~ 521 a.a) full-length human protein.

Sequence
MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    10328

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