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About This Item

Empirical Formula (Hill Notation):
C23H18N2O
CAS Number:
151358-47-3
Molecular Weight:
338.40
MDL number:
MFCD03723253
UNSPSC Code:
12352200
NACRES:
NA.77
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

off-white to pink

solubility

DMSO: 2 mg/mL

storage temp.

−20°C

SMILES string

OC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

InChI

1S/C23H18N2O/c26-16-11-9-15(10-12-16)23(19-13-24-21-7-3-1-5-17(19)21)20-14-25-22-8-4-2-6-18(20)22/h1-14,23-26H

InChI key

QCPDFNWJBQMXLI-UHFFFAOYSA-N

Biochem/physiol Actions

DIM-C-pPhOH is a NR4A1 (Nur77) antagonist that exhibit potent anticancer activity in pancreatic, colon, breast, kidney, and rhabdomyosarcoma cells. DIM-C-pPhOH decreases expression of PAX3-FOXO1A and β1-integrin proteins in Rh30 rhabdomyosarcoma and MDA-MB-231breast cancer cells. DIM-C-pPhOH inhibits migration of Rh30 and MDA-MB-231 cancer cells.
NR4A1 (Nur77) antagonist that exhibit potent anticancer activity

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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