Sign Into View Organizational & Contract Pricing
About This Item
Empirical Formula (Hill Notation):
C41H53N7O8S2 · xC2HF3O2
Molecular Weight:
836.03 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
955 CDK9 PROTAC is a cell penetrant conjugate of the CDK9 inhibitor SNS-032 with new recruiter of the E3 ligase KEAP1 piperlongumine that potently degrades CDK9 in MOLT4 cells. Similarly, to THAL-SNS-032, 955 induces CDK10 degradation. 955 exhibits potent antiproliferative activity in several prostate cancer cell lines including LNCaP, 22RV1, PC3 and DU145 cells.
Cell penetrant, potent and selective CDK9 degrader
Caution
Hygroscopic
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service