Glycoconjugates

Glycoconjugates consist of carbohydrates, or glycans, linked to a protein, lipid, peptide, and other compounds. Glycoconjugates are formed by glycosylation and are involved in various biological processes in organisms. Glycobiology research studies the structure and activity of carbohydrates and glycoconjugates in relation to human health. Understanding how disorders in these processes lead to severe diseases is also relevant to molecular and cellular biology, proteomics, and medicine.
We offer a comprehensive portfolio of glycoconjugates including glycolipids, glycoproteins, and lipopolysaccharides for all your research needs, including extraction, characterization, formulation, chemical/enzymatic modifications involving non-conventional media or activation modes. Discover drug targets for infectious diseases, inflammation, and cancer; develop new potential vaccines against cancer, viral and bacterial infections, and other diseases; and explore other potential uses of glycoconjugates as therapeutics.
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Related Resources
- Article: BIOshell Glycan HPLC Columns
Fast, high-resolution separations of procainamide labeled glycans - dextran ladder, human IgG and cetuximab
- Article: Deglycosylation Kits
Deglycosylation Kits
- Article: Enzymatic Deglycosylation
Enzymatic Deglycosylation Strategies: Sequential hydrolysis of individual monosaccharides from glycans can be useful for the elucidation of the structure and function of the glycan component.
- Article: Glycoprotein Deglycosylation
Information about Glycoprotein deglycosylation. The diversity of oligosaccharide structures, both O-linked and N-linked, often results in heterogeneity in the mass and charge of glycoproteins.
- Article: Glycosaminoglycans and Proteoglycans
There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.
- Article: Glycosphingolipids
Glycosphingolipids
- Article: GPI Anchored Glycoproteins
GPI Anchored Glycoproteins
- Article: Lipopolysacharides
Lipopolysaccharide (LPS) is the major component of the outer membrane of Gram-negative bacteria. Lipopolysaccharide is localized in the outer layer of the membrane and is, in noncapsulated strains, exposed on the cell surface.
- Article: Peptidoglycans
The basic structure of peptidoglycan (PGN) contains a carbohydrate backbone of alternating units of N-acetylglucosamine (GlcNAc) and Nacetylmuramic acid, with the N-acetylmuramic acid residues cross-linked to peptides.
- Article: Purification and Removal of Glycoproteins and Polysaccharides
- Article: Strategies for Deglycosylating N-linked Glycans
Explore various strategies for deglycosylating N-linked glycans involving PNGase F, PNGase A (Glycopeptidase A), and even native and sequential deglycosylation with endoglycosidases like Endoglycosidase H, Endoglycosidase F, and exoglycosidases.
- Brochure: Glycobiology
Glycobiology and glycoproteomics are crucial in life science, with diverse glycoproteins and important roles in cellular communication and physiology.
- Brochure: Glycoconjugates from GlycoNZ
Glycobiology is vital in understanding carbohydrates' role in human health. We offer a wide range of products, including glycoconjugates, and have expanded our portfolio through a partnership with GlycoNZ, offering more opportunities for exploring drug targets for various diseases.
- Selection Guide: Deglycosylation
Complete kits for highly specific deglycosylation.
- Selection Guide: Glycoproteomics Selection Guide — Deglycosylation
Glycoproteomics Selection Guide — Deglycosylation and Glycoproteomics Selection Guide — Labeling and Detection, Quantitation
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