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Viral Vector Upstream Processing

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facet applications:Viral Vector Upstream Processing
Introducing our Novel Sf9 Rhabdovirus-negative (Sf-RVN®) Platform
In this webinar, we discuss our novel Sf9 rhabdovirus-negative (Sf-RVN®) platform, a safer alternative baculovirus expression vector system (BEVS) for the production of adeno-associated viruses (AAV), viral-like particles (VLP), and recombinant proteins.
Turnkey Solutions for Upstream Cell Culture Processes
What could you accomplish if less time could be spent on process development due to rapid cell culture feed screening process? In this webinar, we explore the benefits of feed mixing and use of chemically defined and protein-quality supplements.
Bioreactor Process Development and Scale-Up for Transient Transfection-Based Lentivirus Manufacturing in Suspension Cell Culture
A step-by-step overview of suspension-based, transient transfection bioreactor process development and scaleup of lentivirus production.
Scalability Challenges of Viral Vector Manufacturing
Scaling up viral vector production using adherent cell culture systems is challenging. Learn how suspension cell culture systems benefit large-scale bioprocessing.
Considerations for Development of a Platform Lentivirus Harvest Clarification Process for Cell and Gene Therapy
This article explores a variety of lentivirus harvest clarification options and items for consideration during manufacturing platform development of viral therapy production using suspension cell lines.
Right First Time: Viral Vector Platform Development
Webinar on building integrated platforms for viral vector production and testing.
Next-Gen Raman PAT Platform for Bioprocess Monitoring
Webinar emphasizes process knowledge with real-time monitoring for bioprocess development efficiency.
High Performing Platforms for Lentivirus and AAV Manufacturing
Upstream gene therapy optimization maximizes viral vector titers; partner with technology experts for HEK293, HEK293T, and Sf9 cell solutions.
Development of a Novel Cell Culture Medium for AAV Production With Multiple HEK293 Lineages and Process Optimization
Read our white paper on the development of a novel cell culture medium for AAV production with multiple HEK293 lineages and process optimization.
Scalability Challenges of Viral Vector Manufacturing
Scaling up viral vector production using adherent cell culture systems is challenging. Learn how suspension cell culture systems benefit large-scale bioprocessing.
Development of a Novel Sf9 Rhabdovirus-Negative Cell Line (Sf-RVN®) and Companion Chemically Defined Medium
See how the Sf9 rhabdovirus-free cell line was developed and how we’ve developed a companion chemically-defined insect cell media for protein and viral expression.
Viral Vector Upstream Processing
Complex upstream decisions in viral vector production affect downstream processes. Raw materials, media, and storage choices significantly impact outcomes.
Removing DNA and RNA Using Benzonase Endonuclease During Viral Production
Whether you are developing cell and gene therapies or viral vaccines, removing contaminating nucleic acids is an important part of viral production. The simplest way to do this is to use the Benzonase® endonuclease.
Next-Gen Raman PAT Platform for Bioprocess Monitoring
Webinar emphasizes process knowledge with real-time monitoring for bioprocess development efficiency.
Right First Time: Viral Vector Platform Development
Webinar on building integrated platforms for viral vector production and testing.
Media and Process Development for Seed Train Intensification
Biopharmaceutical media composition webinar optimizes production timelines and productivity.
Riding the Gene Therapy Roller Coaster: Journey through Tech Transfer to Commercialization
Learn how our integrated approach can help you navigate the twists and turns of gene therapy process development and tech transfer all the way through to commercial readiness. This talk will shed light on process development for viral vector manufacturing
Viral Vector Upstream Processing
Complex upstream decisions in viral vector production affect downstream processes. Raw materials, media, and storage choices significantly impact outcomes.
Lentivirus Harvest Clarification Process for Cell & Gene
Explore lentivirus harvest clarification options for viral therapy production using suspension cell lines in manufacturing platform development.
DNA/RNA Removal in Viral Production
Benzonase®endonuclease efficiently removes nucleic acid contaminants from viral production, crucial for cell and gene therapies and vaccines.
Development and Optimization of a Lentivirus Manufacturing Platform
Learn how development of a suspension adapted HEK293T cell line with accompanying cell culture media can maximize lentivirus production for cell and gene therapies.
Cell and Gene Therapy Manufacturing: Upstream Processing for AAV and Lentivirus Platforms
Minimize the complexities of cell and gene therapy production. Switch to upstream viral vector platforms to enhance scalability and simplify GMP manufacturing.
Bioreactor Process Development and Scale-Up for Transient Transfection-Based Lentivirus Manufacturing in Suspension Cell Culture
A step-by-step overview of suspension-based, transient transfection bioreactor process development and scaleup of lentivirus production.
Bioprocessing And Scale-Up Of Suspension HEK293 Cells For AAV Manufacturing
To address scalability challenges of AAV manufacturing, we developed an HEK293 suspension cell line that can be used across many serotypes. Get the data in this article.