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Merck

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

동의어:
DHLAG, HLADG, II, Ia-GAMMA
:
UniProtKB ID:
Clone ID:
  • Human(972) Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(16149) CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Rat(25599) Cd74 molecule, major histocompatibility complex, class II invariant chain
  • chicken(414741) CD74 molecule, major histocompatibility complex, class II invariant chain
  • cow(613384) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic cat(101085953) CD74 molecule, major histocompatibility complex, class II invariant chain
  • dog(479329) CD74 molecule, major histocompatibility complex, class II invariant chain
  • sheep(101102561) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic guinea pig(100735496) CD74 molecule, major histocompatibility complex, class II invariant chain
  • naked mole-rat(101723625) CD74 molecule, major histocompatibility complex, class II invariant chain

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ELISA

Product Number
설명
Human CD74 ELISA, for serum, plasma and cell culture supernatants,
human

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-CD74 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Monoclonal Anti-CD74-Horseradish Peroxidase antibody produced in mouse, clone 6D9,
종별 반응성
human
응용분야
immunofluorescence
western blot
Monoclonal Anti-CD74-FITC antibody produced in mouse, clone 3D7,
종별 반응성
human
응용분야
flow cytometry
western blot
Monoclonal Anti-CD74-R-Phycoerythrin antibody produced in mouse, clone 1B8,
종별 반응성
human
응용분야
immunofluorescence
western blot
Monoclonal Anti-CD74-Atto 594 antibody produced in mouse, clone 6D9,
종별 반응성
human
응용분야
immunofluorescence
western blot

esiRNA

Product Number
설명
MISSION® esiRNA, targeting mouse Cd74,
mouse
MISSION® esiRNA, targeting human CD74,
human