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Merck

CDC25B

cell division cycle 25B

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(994) Summary: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
  • Mouse(12531) cell division cycle 25B
  • Rat(171103) cell division cycle 25B
  • naked mole-rat(101701077) cell division cycle 25B
  • domestic guinea pig(100716851) cell division cycle 25B
  • sheep(101120511) cell division cycle 25 homolog B (S. pombe)
  • domestic cat(101092757) cell division cycle 25 homolog B (S. pombe)
  • cow(505847) cell division cycle 25 homolog B (S. pombe)
  • Horse(100052425) cell division cycle 25 homolog B (S. pombe)
  • dog(485790) cell division cycle 25 homolog B (S. pombe)

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-CDC25B antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
mouse
Aplicación
western blot
Anti-phospho-CDC25B (pSer323) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-phospho-CDC25B (pSer353) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-phospho-CDC25B (pSer353) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Descripción
Especie
NSC 663284, ≥98% (HPLC), solid,
Especie
human
NSC 95397, ≥97% (HPLC),
Especie
human

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human CDC25B,
Especie
human
MISSION® esiRNA, targeting mouse Cdc25b,
Especie
mouse